Two blood-filled test tubes with red caps.

Should You Get a PSA Test?

What You Need to Know About Prostate Cancer Screening

If you are a man over 40, you may have heard about the PSA test. It is a blood test that looks for signs of prostate cancer.

But when should you get it? And does everyone need it?

The answer is not simple.

What Is a PSA Test?

PSA stands for prostate-specific antigen. It is a protein made by the prostate. Higher levels in the blood can be a sign of prostate cancer.

But PSA can also be high for other reasons, including:

  • Infection
  • Inflammation
  • An enlarged prostate
  • Testosterone therapy

This is why PSA is not a perfect test.

A Quick Note on Testosterone

If you are using testosterone therapy, your PSA levels may go up. This does not mean you have cancer.

Testosterone can cause the prostate to grow slightly, especially in the early stages of treatment. That can lead to a mild increase in PSA.

Your doctor should monitor your PSA regularly while you are on testosterone. If the number rises too quickly, further evaluation may be needed. But in many cases, small changes are expected and harmless.

Why Guidelines Differ

There is no universal agreement on PSA screening.

Here are some general recommendations:

  • The US Preventive Services Task Force says men age 55 to 69 may choose to screen after talking with a doctor
  • The American Urological Association suggests screening from age 50 for average risk
  • The American Cancer Society recommends:
    • Age 50 for average risk
    • Age 45 for higher risk (such as Black men or those with a family history)
    • Age 40 for strong family history

Why PSA Is Controversial

PSA testing can help find cancer early. But it can also lead to:

  • False positives
  • Unnecessary biopsies
  • Worry and stress
  • Overtreatment of slow-growing cancers

Some men benefit. Others may be harmed. That is why screening should be personalized.

So What Should You Do?

Talk with your doctor.

Together, you should consider:

  • Your age
  • Family history
  • Race and risk level
  • Whether you are on testosterone therapy
  • Your personal goals and concerns

At Ace Longevity, we guide patients through these decisions with care, clarity, and science.

Wondering if PSA testing is right for you?
Schedule a visit and let’s talk through the risks, the benefits, and what makes the most sense for you.